1. DGAT1-IN-1

DGAT1-IN-1 

目录号: HY-12425 纯度: 95。14%
产品使用指南

DGAT1-IN-1是高效DGAT1抑制剂,IC50值低于10nM(Hep3B细胞过表达DGAT1裂解物测得)。

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DGAT1-IN-1 Chemical Structure

DGAT1-IN-1 Chemical Structure

CAS No. : 1449779-49-0

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥4247 In-stock
2 mg ¥2333 In-stock
5 mg ¥3500 In-stock
10 mg ¥5000 In-stock
50 mg ¥15000 In-stock
100 mg ¥21000 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1). IC50 value: < 10 nM Target: DGAT1 inhibitor Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation By Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (36.26 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8130 mL 9.0652 mL 18.1304 mL
5 mM 0.3626 mL 1.8130 mL 3.6261 mL
10 mM 0.1813 mL 0.9065 mL 1.8130 mL
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液。
References
  • [1].

Molecular Weight

551。56

Formula

C₃₀H₂₈F₃N₃O₄

CAS No.

1449779-49-0

SMILES

OC(C[C@H]1CC[C@H](C2=CC=C(C3=CN4C=C(C(NCC5=CC=C(OC(F)(F)F)C=C5)=O)N=C4C=C3)C=C2)CC1)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • [1].

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
DGAT1-IN-1
目录号:
HY-12425
需求量:

DGAT1-IN-1

Cat. No.: HY-12425

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